National Heart, Lung, and Blood Institute
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Robert Lederman

Senior Investigator (Cardiology (incl. cardiovascular diseases))

Bethesda, Maryland, USA

Publications

  • LAMPOON to Facilitate Tendyne Transcatheter Mitral Valve Replacement.
  • Bedside Modification of Delivery System for Transcatheter Transseptal Mitral Replacement With POULEZ System and SAPIEN-3 Valve.
  • Troubleshooting transcaval access: Honoring our commitments
  • Transcatheter Electrosurgical Laceration and Stabilization of Failed MitraClip[s]/SAPIEN M3 for Treatment of Failed MitraClip
  • Transcatheter Electrosurgery: A Narrative Review
  • Opportunities in Interventional and Diagnostic Imaging by Using High-Performance Low-Field-Strength MRI.
  • Transcaval Access and Closure Best Practices
  • Anterior Leaflet Laceration to Prevent Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Replacement.
  • BI-SILICA During Transcatheter Aortic Valve Replacement for Noncalcific Aortic Insufficiency: Initial Human Experience.
  • X-ray fused with MRI guidance of pre-selected transcatheter congenital heart disease interventions.
  • Sheathless Transcaval Transcatheter Aortic Valve Implantation Through an Abdominal Aortic Graft.
  • A cardiovascular magnetic resonance (CMR) safe metal braided catheter design for interventional CMR at 1.5 T: freedom from radiofrequency induced heating and preserved mechanical performance.
  • Postinfarction Ventricular Septal Defect Closure.
  • The Fate of Transcaval Access Tracts: 12-Month Results of the Prospective NHLBI Transcaval Transcatheter Aortic Valve Replacement Study.
  • LAMPOON transseptal mitral valve in ring.
  • Adventures across the second dimension: Predicting left ventricular outflow tract obstruction following transcatheter mitral valve replacement.
  • "Rescue" LAMPOON to Treat Transcatheter Mitral Valve Replacement-Associated Left Ventricular Outflow Tract Obstruction.
  • Preventing Coronary Obstruction During Transcatheter Aortic Valve Replacement: From Computed Tomography to BASILICA.
  • The BASILICA Trial: Prospective Multicenter Investigation of Intentional Leaflet Laceration to Prevent TAVR Coronary Obstruction.
  • International LAMPOON: first European experience with laceration of the anterior mitral valve leaflet prior to transseptal transcatheter mitral valve implantation.
  • Predicting Left Ventricular Outflow Tract Obstruction Despite Anterior Mitral Leaflet Resection: The "Skirt NeoLVOT".
  • Blood volume measurement using cardiovascular magnetic resonance and ferumoxytol: preclinical validation.
  • Acousto-Optic Catheter Tracking Sensor for Interventional MRI Procedures.
  • TAVR Roulette: Caution Regarding BASILICA Laceration for TAVR-in-TAVR.
  • Warning: Alcohol Before TMVR May Cause Serious Injury or Loss of Life.
  • Tip-to-Base LAMPOON to Prevent Left Ventricular Outflow Tract Obstruction in Valve-in-Valve Transcatheter Mitral Valve Replacement.
  • Transcatheter Electrosurgery: JACC State-of-the-Art Review.
  • Pachyderm-Shape Guiding Catheters to Simplify BASILICA Leaflet Traversal.
  • Unnatural milieu: Thrombus after transcatheter mitral valve replacement
  • Dynamic nature of the LVOT following transcatheter mitral valve replacement with LAMPOON: new insights from post-procedure imaging
  • Transcatheter pledget‐assisted suture tricuspid annuloplasty (PASTA) to create a double‐orifice valve
  • First‐in‐human transcatheter pledget‐assisted suture tricuspid annuloplasty for severe tricuspid insufficiency
  • Sickle related events following cardiac catheterisation: risk implication for other invasive procedures
  • BATMAN—Savior or vigilante?
  • Interventional-cardiovascular MR: Role of the interventional MR technologist
  • X-ray fused with magnetic resonance imaging to guide endomyocardial biopsy of a right ventricular mass
  • Transcaval Access and Closure for Transcatheter Aortic Valve Replacement: A Prospective Investigation
  • Anatomic Suitability for Transcaval Access Based on Computed Tomography
  • Predicting LVOT Obstruction After TMVR
  • Real-Time Magnetic Resonance Imaging Guidance Improves the Diagnostic Yield of Endomyocardial Biopsy
  • Exercise magnetic resonance imaging is a gas
  • Magnetic Resonance Imaging-Guided Transcatheter Cavopulmonary Shunt
  • Transcatheter myocardial needle chemoablation during real-time magnetic resonance imaging
  • Guidewire electrosurgery‐assisted trans‐septal puncture
  • Transcatheter electrosurgery in bipolar or monopolar modes
  • CRT-400.10 Real-time MRI Guidance Improves the Diagnostic Yield of Endomyocardial Biopsy Compared With X-ray Fluoroscopy
  • Percutaneous transaxillary access for TAVR: Another opportunity to stay out of the chest
  • Physiological Recording in the MRI Environment (PRiME): MRI-Compatible Hemodynamic Recording System
  • Transcaval access for the emergency delivery of 5.0 liters per minute mechanical circulatory support in cardiogenic shock
  • Advances in Transcatheter Electrosurgery for Treating Valvular Heart Disease
  • Real-time MRI-guided right heart catheterization in adults using passive catheters
  • Letter by Lederman et al regarding article, "MRI-induced stent dislodgment soon after left main coronary artery stenting".
  • Fully percutaneous transthoracic left atrial entry and closure as a potential access route for transcatheter mitral valve interventions
  • MRI-induced stent dislodgment soon after left main coronary artery stenting
  • MRI roadmap-guided transendocardial delivery of exon-skipping recombinant adeno-associated virus restores dystrophin expression in a canine model of Duchenne muscular dystrophy
  • Parallel transmit excitation at 1.5 T based on the minimization of a driving function for device heating
  • Real-time magnetic resonance imaging (MRI)-guided intervention
  • Brucella arteritis: clinical manifestations, treatment, and prognosis
  • Interventional CMR: Clinical Applications and Future Directions
  • Lost in Translation
  • MRI Catheterization in Cardiopulmonary Disease
  • Roadmaps show the way: Coregistration to enhance structural heart interventions
  • Integration of cardiac and respiratory motion into MRI roadmaps fused with x-ray
  • Reply
  • Right heart catheterization from the arm: Back to first principles
  • Transcaval Aortic Access for Percutaneous Thoracic Aortic Aneurysm Repair: Initial Human Experience
  • Dual echo positive contrast bSSFP for real-time visualization of passive devices duringmagnetic resonance guided cardiovascular catheterization
  • Percutaneous MR guided direct left atrial access to deliver large interventional devices
  • Transcatheter bidirectional Glenn shunt guided by real-time MRI
  • Two channel passive visualization of a nitinol guidewire with iron markers
  • Transcaval access for TAVR across a polyester aortic graft
  • Aortic Access From the Vena Cava for Large Caliber Transcatheter Cardiovascular Interventions
  • TCT-124 A novel appliance for transcatheter mitral cerclage annuloplasty
  • TCT-127 Trans-Auricular Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA)
  • Caval-Aortic Access to Allow Transcatheter Aortic Valve Replacement in Otherwise Ineligible Patients
  • TCT-158 Fully Percutaneous Transthoracic Left Atrial Entry and Closure to Deliver Large Caliber Transcatheter Mitral Valve Implants
  • Image Fusion Guided Device Closure of Left Ventricle to Right Atrium Shunt: Figure.
  • MR guided right heart catheterization - the NIH experience
  • Planning Transcaval Access Using CT for Large Transcatheter Implants
  • Stiffness-matched segmented metallic guidewire for interventional cardiovascular MRI
  • Realtime MR guided endomyocardial biopsy with an active visualization bioptome
  • Positive contrast spiral imaging of a nitinol guidewire
  • An efficient, free-breathing protocol for MR right heart catheterization
  • Provocative MRI catheterization
  • Technologist primer for MRI right heart catheterization: the NIH and CNMC experience
  • Dual echo bSSFP for real-time positive contrast of passive nitinol guidewires in MRI-guided cardiovascular interventions
  • Interactive black blood preparation for interventional cardiovascular MRI
  • How to perform transcaval access and closure for transcatheter aortic valve implantation
  • Intentional Right Atrial Exit and Carbon Dioxide Insufflation to Facilitate Subxiphoid Needle Entry Into the Empty Pericardial Space
  • Positive contrast spiral imaging for visualization of commercial nitinol guidewires with reduced heating
  • Concordance and diagnostic accuracy of vasodilator stress cardiac MRI and 320-detector row coronary CTA
  • Real-time imaging system using a 12-MHz forward-looking catheter with single chip CMUT-on-CMOS array
  • Real-time distortion correction of spiral and echo planar images using the gradient system impulse response function
  • Magnetic Resonance Sequences and Rapid Acquisition for MR-Guided Interventions
  • Effect of mechanical assistance of the systemic ventricle in single ventricle circulation with cavopulmonary connection
  • CRT-817 Intentional Right Atrial Exit For Microcatheter Infusion Of Pericardial Carbon Dioxide Or Iodinated Contrast To Facilitate Sub-xiphoid Access
  • CRT-821 Fully Percutaneous Transthoracic Left Atrial Access To Deliver Large Interventional Devices
  • Transatrial Intrapericardial Tricuspid Annuloplasty
  • Segmented nitinol guidewires with stiffness-matched connectors for cardiovascular magnetic resonance catheterization: preserved mechanical performance and freedom from heating
  • Intentional right atrial exit for microcatheter infusion of pericardial carbon dioxide or iodinated contrast to facilitate sub-xiphoid access
  • Pressure-wire based assessment of microvascular resistance using calibrated upstream balloon obstruction: a predictor of myocardial viability.
  • Prophylactic, standby, or rescue support for high-risk PCI: Who knows?
  • Bright-blood T 2-weighted MRI has high diagnostic accuracy for myocardial hemorrhage in myocardial infarction a preclinical validation study in swine
  • Transthoracic delivery of large devices into the left ventricle through the right ventricle and interventricular septum: Preclinical feasibility
  • Intracoronary infusion of autologous mononuclear cells from bone marrow or granulocyte colony-stimulating factor-mobilized apheresis product may not improve remodelling, contractile function, perfusion, or infarct size in a swine model of large myocardial infarction
  • RT-GROG: parallelized self-calibrating GROG for real-time MRI
  • Interventional MRI using multiple 3D angiography roadmaps with real-time imaging
  • NT5E Mutations and Arterial Calcifications
  • Mitral Cerclage Annuloplasty, A Novel Transcatheter Treatment for Secondary Mitral Valve Regurgitation
  • Interventional Cardiovascular Magnetic Resonance Imaging
  • Recanalization of chronic peripheral artery occlusions: Moving forward by looking sideways
  • Legs bend: Why dynamic angiography is important
  • Interventional Cardiovascular MRI
  • Interventional Cardiovascular Magnetic Resonance
  • Real-Time Interactive MRI for Guiding Cardiovascular Surgical Interventions
  • Real-time catheter-directed MRA with effective background suppression and persistent rendering
  • Efficient implementation of hardware-optimized gradient sequences for real-time imaging
  • A practical global distortion correction method for an image intensifier based x-ray fluoroscopy system
  • Virtual dye angiography: Flow visualization for MRI-guided interventions
  • Robust automatic rigid registration of MRI and X-ray using external fiducial markers for XFM-guided interventional procedures
  • Interventional cardiovascular MR—The next stage in pediatric cardiology
  • VEGFR1/CXCR4-positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1-dependent mechanism
  • Interventional cardiovascular magnetic resonance: still tantalizing
  • Active delivery cable tuned to device deployment state: Enhanced visibility of nitinol occluders during preclinical interventional MRI
  • Whole shaft visibility and mechanical performance for active MR catheters using copper-nitinol braided polymer tubes
  • Getting Closer for High-Resolution Vascular MRI⁎⁎Editorials published in JACC: Cardiovascular Imaging reflect the views of the authors and do not necessarily represent the views of JACC: Cardiovascular Imaging or the American College of Cardiology.
  • Antegrade Percutaneous Closure of Membranous Ventricular Septal Defect Using X-Ray Fused With Magnetic Resonance Imaging
  • Direct Percutaneous Left Ventricular Access and Port Closure
  • Closed-Chest Transthoracic Magnetic Resonance Imaging-Guided Ventricular Septal Defect Closure in Swine
  • Technology preview: X-ray fused with magnetic resonance during invasive cardiovascular procedures
  • Simultaneous imaging of myocardial motion and chamber blood flow with SPAMM n' EGGS (spatial modulation of magnetization with encoded gradients for gauging speed)
  • Visualization of active devices and automatic slice repositioning (“SnapTo”) for MRI-guided interventions
  • Closed chest transthoracic perventricular ventricular septal defect closure under real-time MRI
  • An interleaved-navigator projection dual-echo bSSFP sequence for respiratory self-gated imaging
  • Visualization of dynamic active devices via adaptive undersampled projection imaging
  • Real-time MRI guided percutaneous transthoracic left ventricular access and closure
  • Golden-step phase encoding for flexible realtime Cardiac MRI
  • A deflectable guiding catheter for real-time MRI-guided interventions
  • Virtual Dye Angiography: flow visualization for MRI-guided interventions using endogenous contrast
  • MRI-guided vascular access with an active visualization needle
  • MRI active guidewire with an embedded temperature probe and providing a distinct tip signal to enhance clinical safety
  • Adaptive noise cancellation to suppress electrocardiography artifacts during real-time interventional MRI
  • Limitations of closing percutaneous transthoracic ventricular access ports using a commercial collagen vascular closure device
  • Active two-channel 0.035″ guidewire for interventional cardiovascular MRI
  • Real-time cardiovascular magnetic resonance subxiphoid pericardial access and pericardiocentesis using off-the-shelf devices in swine
  • Pressure-wire based assessment of microvascular resistance using calibrated upstream balloon obstruction
  • 109 Antegrade percutaneous closure of membranous ventricular septal defect using X-Ray fused with MRI (XFM)
  • Experimental Model of Large Pulmonary Embolism Employing Controlled Release of Subacute Caval Thrombus in Swine
  • 2107 "Bright when tight": a wireless resonant staple for interventional MRI
  • Real-Time MR Imaging–guided Laser Atrial Septal Puncture in Swine
  • Balloon angioplasty or nitinol stents for peripheral-artery disease [4]
  • Magnetic resonance imaging-guided vascular interventions
  • Cardiovascular interventional magnetic resonance imaging
  • Erratum: Real-time volume rendered MRI for interventional guidance (Journal of Cardiovascular Magnetic Resonance (2002) 4:4 (431-442))
  • Distortion correction, calibration, and registration: Towards an integrated MR and x-ray interventional suite
  • Angiogenesis with recombinant fibroblast growth factor-2 for claudication [4] (multiple letters)
  • Real-time magnetic resonance imaging-guided endovascular recanalization of chronic total arterial occlusion in a swine model
  • Real-time magnetic resonance imaging to guide pediatric endovascular procedures
  • Targeted endoniyocardial injections of therapeutic cells using X-ray fused with MRI guidance
  • Real-time magnetic resonance imaging-guided stenting of aortic coarctation with commercially available catheter devices in swine
  • X-ray fused with magnetic resonance imaging (XFM) to target endomyocardial injections: Validation in a swine model of myocardial infarction
  • Delivery and tracking of therapeutic cell preparations for clinical cardiovascular applications
  • Magnetic resonance image-guided trans-septal puncture in a swine heart
  • Magnetic resonance imaging-guided vascular interventions
  • Real-time, Interactive MRI for cardiovascular interventions
  • Delivery and tracking of therapeutic cell preparations for clinical cardiovascular applications
  • Delayed Hyperenhancement Imaging without ECG-Gating or Breath Holding using Fast Interactive MRI [Abstract]
  • Interactive undersampled projection reconstruction for active catheter imaging, with adaptable temporal resolution and catheter-only views
  • Real-time accelerated interactive MRI with adaptive TSENSE and UNFOLD
  • Real-time, Interactive MRI for Cardiovascular Interventions1
  • MRI-guided drug and cell injection therapies for heart disease
  • Angiogenesis with recombinant fibroblast growth factor-2 for claudication
  • Advances in interventional cardiovascular MRI
  • Interventional Cardiovascular Magnetic Resonance Imaging
  • Advances in interventional cardiovascular MRI
  • Intrinsic Conflicts of Interest in Clinical Research: A Need for Disclosure
  • The cardiovascular interventional MRI suite
  • Testing clinical therapeutic angiogenesis using basic fibroblast growth factor (FGF-2)
  • Magnetic resonance image-guided trans-septal puncture in a swine heart
  • Magnetic resonance imaging and its role in myocardial regenerative therapy
  • Blunt atrial transseptal puncture using excimer laser in swine
  • Magnetic Resonance Imaging-guided Vascular Interventions
  • MRI‐guided myocardial cell therapy
  • Measurement of skeletal muscle perfusion during postischemic reactive hyperemia using contrast-enhanced MRI with a step-input function
  • Undersampled projection reconstruction for active catheter imaging with adaptable temporal resolution and catheter-only views
  • Usefulness of translesional pressure gradient and pharmacological provocation for the assessment of intermediate renal artery disease
  • Real-time MRI guided atrial septal puncture and balloon septostomy in swine
  • Real-time interactive MRI-guided cardiac surgery: Aortic valve replacement using a direct apical approach
  • Regional angiogenesis with vascular endothelial growth factor (VEGF) in peripheral arterial disease: Design of the RAVE trial
  • Beating Heart Aortic Valve Replacement Using Real-Time MRI Guidance
  • Real-time magnetic resonance imaging guidance for endograft delivery in a porcine model of abdominal aortic aneurysm
  • Real-time magnetic resonance imaging for integrated identification, targeting, and injection of labeled stem cells to porcine myocardial infarction
  • High-resolution 3D arteriography of chronic total peripheral occlusions using aT1-W turbo spin-echo sequence with inner-volume imaging
  • Interventional cardiovascular procedures guided by real-time MR imaging: An interactive interface using multiple slices, adaptive projection modes and live 3D renderings
  • Coronary artery aneurysms in patients with hyper IgE recurrent infection syndrome
  • Reduced field of view and undersampled PR combined for interventional imaging of a fully dynamic field of view
  • Percutaneous Stenting of Incidental Unilateral Renal Artery Stenosis: Decision Analysis of Costs and Benefits
  • Invasive human magnetic resonance imaging: Feasibility during revascularization in a combined XMR suite
  • Imaging of myocardial infarction for diagnosis and intervention using real-time interactive MRI without ECG-gating or breath-holding
  • Real-Time Magnetic Resonance-Guided Endovascular Repair of Experimental Abdominal Aortic Aneurysm in Swine
  • Coronary artery flow imaging with an intraluminal array
  • Percutaneous stenting of incidental unilateral renal artery stenosis: decision analysis of costs and benefits
  • Catheter-based endomyocardial injection with real-time magnetic resonance imaging
  • Intrinsic conflicts of interest in clinical research: A need for disclosure
  • Primary renal artery stenting: characteristics and outcomes after 363 procedures
  • Cardiovascular involvement in AIDS
  • Mesenchymal 'stem cell rescue' for myocardial disease
  • Blood speed imaging with an intraluminal array
  • Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells
  • Catheter-based endomyocardial injection with real-time magnetic resonance imaging
  • Detection of atherosclerosis using a novel positron-sensitive probe and 18-fluorodeoxyglucose (FDG)
  • Regional Angiogenesis with Vascular Endothelial Growth Factor in Peripheral Arterial Disease: A Phase II Randomized, Double-Blind, Controlled Study of Adenoviral Delivery of Vascular Endothelial Growth Factor 121 in Patients with Disabling Intermittent Claudication
  • Magnetic Resonance Fluoroscopy Allows Targeted Delivery of Mesenchymal Stem Cells to Infarct Borders in Swine
  • Intrinsic conflicts of interest in clinical research: a need for disclosure
  • Real-time accelerated interactive MRI with adaptive TSENSE and UNFOLD
  • Regional Angiogenesis with Vascular Endothelial Growth Factor (VEGF) in peripheral arterial disease: Design of the RAVE trial
  • Serial cardiac magnetic resonance imaging of injected mesenchymal stem cells
  • Testing clinical therapeutic angiogenesis using basic fibroblast growth factor (FGF-2)
  • Incomplete retention after direct myocardial injection
  • Mesenchymal 'stem cell rescue' for myocardial disease
  • Real-time volume rendered MRI for interventional guidance
  • Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial
  • Design of the therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (TRAFFIC) trial
  • Detection of atherosclerosis using a novel positron-sensitive probe and 18-fluorodeoxyglucose (FDG)
  • Acute hemodynamic changes during carotid artery stenting
  • Kissing stents in the aortic bifurcation
  • Superimposed stents in the management of acute recoil after Palmaz-Schatz stenting
  • Cardiovascular involvement in AIDS
  • Implications of smoking status on the response to therapeutic angiogenesis in peripheral artery disease: findings from the therapeutic angiogenesis with FGF-2 for intermittent claudication (TRAFFIC) trial
  • Incomplete retention after direct myocardial injection
  • Primary renal artery stenting: Characteristics and outcomes after 363 procedures
  • Cardiovascular Interventional MRI
  • Real-Time Volume Rendered MRI for Interventional Guidance
  • Superimposed stents in the management of acute recoil after Palmaz-Schatz stenting
  • Kissing stents in the aortic bifurcation
  • Design of the therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (TRAFFIC) trial
  • Real-time MRI angioplasty using intravascular guidewire coils
  • Intravascular guidewire coil facilitated invasive real-time magnetic resonance arteriography
  • Acute hemodynamic changes during carotid artery stenting
  • Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): a randomised trial

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Co-workers & collaborators

  • Rim Halaby

  • Christopher Bruce

Robert Lederman's public data